| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5500991 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 38 Pages |
Abstract
IGF-1R signalling contributes to T cell dependent inflammation in arthritis. Inhibition of IGF-1R on the level of insulin receptor substrates alleviates arthritis by restricting IL6-dependent formation of Th17 cells and may open for new treatment strategies in RA.
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Authors
Malin C. Erlandsson, Sofia Töyrä Silfverswärd, Mitra Nadali, Minna Turkkila, Mattias N.D. Svensson, Ing-Marie Jonsson, Karin M.E. Andersson, Maria I. Bokarewa,