| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5501036 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 42 Pages |
Abstract
Taken together, our data suggest a key role of TRPC6 channels in the mediation of insulin-dependent activation of PKGIα signaling pathways. Overall, we have identified a potentially important mechanism that may explain disturbances in filtration barrier permeability in many diseases with increased expression of TRPC6 and chronic Ca2 + overload.
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Authors
Dorota Rogacka, Irena Audzeyenka, Patrycja Rachubik, MichaÅ RychÅowski, MaÅgorzata Kasztan, Maciej Jankowski, Stefan Angielski, Agnieszka Piwkowska,