| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5501058 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 35 Pages |
Abstract
The results confirm the existence of an asthma severity metabolome. However, differences in the metabolomic profiles of the three lung function characteristics studied, suggest that refinement of both phenotype classification and metabolite selection should be a priority as the field of asthma metabolomics progresses.
Keywords
AHRFEV1/FVC ratioPLS-DAROCLC-MSAUCFEV1/FVCAsthmatricarboxylic acidpartial least squares-discriminant analysisLung functionMetabolomicsarea under the curvereceiver operator characteristicairway hyper-responsivenessAirway hyperresponsivenessTCA cycleliquid chromatography tandem mass spectrometryquality control
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Authors
Rachel S. Kelly, Yamini Virkud, Rachel Giorgio, Juan C. Celedón, Scott T. Weiss, Jessica Lasky-Su,