| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5501167 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 11 Pages |
Abstract
Our results indicate that rod photoreceptors, following UPR activation during adRP progression, secrete TNFa and signal a self-destructive program to the cones, resulting in their cell death. TNFa therefore holds promise as a therapeutic target for treatment of adRP.
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Authors
Tapasi Rana, Pravallika Kotla, Roderick Fullard, Marina Gorbatyuk,