Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5501178 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 37 Pages |
Abstract
Increasing triglyceride content in the core of an HDL particle augments apolipoprotein release from the HDL surface. This released protein can bind to other HDL, get degraded or get misfolded in amyloid.301
Keywords
DSCnormolipidemicnHDLrHDLLCATVLDLLPLSAAPAGEHDLMMPSECCETPreconstituted HDLhigh-density lipoproteinamyloid Aapoapolipoproteinpolyacrylamide gel electrophoresisSize-exclusion chromatographyThTTrioleintriglycerideThioflavin TDiabetes mellitusSAA, Serum amyloid ALipoprotein lipasevery-low density lipoproteinElectron microscopywild typecholesterol ester transfer proteinDifferential scanning calorimetryCholesterol esterunesterified cholesterol
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Authors
Shobini Jayaraman, Jose Luis Sánchez-Quesada, Olga Gursky,