Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center

Article ID	Journal	Published Year	Pages	File Type
5501665	Free Radical Biology and Medicine	2017	11 Pages	PDF

Keywords

DOPC SAPC TLCL PCOOH TOCl SPR analysis PHGPx Dem GPx4 BSO Cys GPX RMSD VMD SEC Surface plasmon resonance SPR Molecular dynamics visual molecular dynamics Selenocysteine Cysteine Membrane phosphatidyl choline root mean square deviation Phosphatidylcholine hydroperoxide Lipid peroxidation Cardiolipin Glutathione peroxidases

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center

Authors

Giorgio Cozza, Monica Rossetto, Valentina Bosello-Travain, Matilde Maiorino, Antonella Roveri, Stefano Toppo, Mattia Zaccarin, Lucio Zennaro, Fulvio Ursini,