| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5501679 | Free Radical Biology and Medicine | 2017 | 43 Pages |
Abstract
AMPK and AKT were activated by electroacupuncture treatment, further triggered GLUTs to increase the energy metabolism, and negatively regulated mTOR to induce autophagy and eliminate Aβ deposition, which delayed the cognitive impairments, particularly in learning and memory ability in AD model mice.344
Keywords
AβMWMNORAMPK18F-FDGmTOR18F-fluoro-2-deoxy-d-glucoseTHsamyloid-betaAktcognitive impairmentElectroacupunctureIHCImmunohistochemistryAlzheimer's diseaseEnzyme-linked immunosorbent assayELISAPositron emission tomographyNovel object recognitionMorris water mazeGlucose metabolismmammalian target of rapamycinPETadenosine monophosphate-activated protein kinase
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Authors
Weilin Liu, Peiyuan Zhuo, Long Li, Hao Jin, Bingbing Lin, Yingzheng Zhang, Shengxiang Liang, Jie Wu, Jia Huang, Zhifu Wang, Ruhui Lin, Lidian Chen, Jing Tao,