Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance

Article ID	Journal	Published Year	Pages	File Type
5501689	Free Radical Biology and Medicine	2017	27 Pages	PDF

Keywords

ERK PKB NTS nNOS WKY IRS eNOS PI3K MAPK insulin insulin receptor substrate CNS Type-2 diabetes insulin receptor substrate 1 endothelial nitric oxide synthase neuronal nitric oxide synthase central nervous system Shr Heart rate Fructose Phosphatidylinositol 3-kinase Hypertension Blood pressure MEK Wistar-Kyoto rats Spontaneously hypertensive rats Nitric oxide Nucleus tractus solitarii mitogen-activated protein kinase extracellular signal-regulated kinases

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance

Authors

Pei-Wen Cheng, Yu-Te Lin, Wen-Yu Ho, Pei-Jung Lu, Hsin-Hung Chen, Chi-Cheng Lai, Gwo-Ching Sun, Tung-Chen Yeh, Michael Hsiao, Ching-Jiunn Tseng, Chun-Peng Liu,