Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity

Article ID	Journal	Published Year	Pages	File Type
5501694	Free Radical Biology and Medicine	2017	10 Pages	PDF

Keywords

OXPHOS ROX ADP FCS ETs GSSG FCCP PCP 2-deoxy-d-glucose ECAR Bcl-xL GSH PPP antimycin A oligomycin OMM Digitonin Residual oxygen consumption Omy 2-DG Adenosine Triphosphate ATP adenosine diphosphate AMA Oxidative stress Mitochondrial respiration Room temperature Rot Rotenone fetal calf serum Succinate cytochrome c electron transfer system endoplasmic reticulum DIG outer mitochondrial membrane Oxidative phosphorylation malate pentose phosphate pathway Mitochondria NAD knockout extracellular acidification rate NAD, nicotinamide adenine dinucleotide reduced glutathione SUIT Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone glutamate

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity

Authors

Annika Pfeiffer, Julia Schneider, Diones Bueno, Amalia Dolga, Timo-Daniel Voss, Jan Lewerenz, Verena Wüllner, Axel Methner,