Potential role of ferric hemoglobin in MS pathogenesis: Effects of oxidative stress and extracellular methemoglobin or its degradation products on myelin components

Article ID	Journal	Published Year	Pages	File Type
5501703	Free Radical Biology and Medicine	2017	10 Pages	PDF

Keywords

HRP 3-[N-morpholino]propanesulphonic acid MDA Hpx oxyHb MOPS A.U.TBST EAE hpt TBARS TBS IPTG TBA MBP PBS AMP FPLC DMSO ROS Hydrogen peroxide Ampicillin EDTA Ethylenediaminetetraacetic acid Thiobarbituric acid sodium dodecyl sulphate-polyacrylamide gel electrophoresis SDS-PAGE Lipid oxidation Protein oxidation isopropyl β-D-thiogalactopyranoside Tris-buffered saline Oxidative stress CNS dimethylsulphoxide CAM BBB fast protein liquid chromatography central nervous system lysogeny broth malondialdehyde Blood-brain barrier metHb Phosphate-buffered saline thiobarbituric acid-reactive substances Multiple sclerosis Myelin Haptoglobin Heme Hemopexin Hemoglobin Hemin Heme-oxygenase H2O2 arbitrary units Horseradish peroxidase Myelin basic protein Chloramphenicol Reactive species Reactive oxygen species

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Potential role of ferric hemoglobin in MS pathogenesis: Effects of oxidative stress and extracellular methemoglobin or its degradation products on myelin components

Authors

Vladimir V. Bamm, Mary E.L. Henein, Shannon L.J. Sproul, Danielle K. Lanthier, George Harauz,