Role of oxidative stress in cardiovascular disease outcomes following exposure to ambient air pollution

Article ID	Journal	Published Year	Pages	File Type
5501721	Free Radical Biology and Medicine	2017	79 Pages	PDF

Keywords

DHT MMP Jnk EPC PM2.5 PAH PM10 CAT HDL tPA NADPH GST NAC GPX HO-1 ICAM-1 vWF DEP TAC iNOS HUVEC DCFH-DA eNOS 1-OHP GSTM1 particulate matter less than 10 μm in diameter particulate matter less than 2.5 μm in diameter ET-1 TLR BMSC Hcy BSO 3-NT PAI-1 LDP sVCAM-1 LVM QTc VCAM-1 PCO MACE oxLDL sP-selectin sICAM-1 LVDP ETA LVEDP Hemeoxygenase-1 LOX-1 15-F2t-IsoP 15-F2t-isoprostane Phosphorylated protein kinase B mDNA MDA 8-oxodGuo TNF soluble VCAM-1 c-Jun NH2-terminal kinases Environmentally persistent free radicals nicotinamide adenine dinucleotide phosphate, reduced QT interval 1-hydroxypyrene 3-nitrotyrosine Mitochondrial DNA HRV ERK1/2 I/R MAPK N-acetylcysteine p-Akt Hydrogen peroxide Gaseous pollutants Ambient air pollution Angiotensin II ACh Acetylcholine endothelin-1 Ozone diesel exhaust ischemia/reperfusion HAEC interleukin BALF Left ventricular developed pressure buthionine sulphoximine cardiovascular disease Metabolic disease EPR Electron paramagnetic resonance Oxidative stress Toll-like receptor Left ventricular mass GEE Soluble ICAM-1 major adverse cardiovascular event spontaneously hypertensive intratracheal Autonomic nervous system Ang II dihydroethidium dichlorodihydrofluorescein diacetate Diabetes mellitus diesel exhaust particle particulate matter Superoxide anion radical ANS SOD human aortic endothelial cell Microvascular endothelial cell Human umbilical vein endothelial cell bone marrow stem cell Endothelial progenitor cell inducible nitric oxide synthase endothelial nitric oxide synthase Metabolic syndrome Superoxide dismutase Total antioxidant capacity Tissue factor Von Willebrand factor Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)tumor necrosis factor left ventricular end diastolic pressure Blood pressure tissue plasminogen activator high density lipoprotein Oxidized low-density lipoprotein low density lipoprotein Matrix metalloprotease malondialdehyde Bronchoalveolar lavage fluid MeS Insulin resistance carbon monoxide Plasminogen activator inhibitor-1 Intercellular adhesion molecule 1 vascular cell adhesion molecule mitogen activated kinase MicroRNA MiRNA heart rate variability NO2 Nitrogen dioxide Nitric oxide Nickel homocysteine H2O2 Polycyclic aromatic hydrocarbon Oxidative potential Catalase Carbon black Black carbon protein carbonyl CaP extracellular signal-regulated kinase Glutathione transferase glutathione peroxidase

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Role of oxidative stress in cardiovascular disease outcomes following exposure to ambient air pollution

Authors

Frank J. Kelly, Julia C. Fussell,