Silymarin protects against renal injury through normalization of lipid metabolism and mitochondrial biogenesis in high fat-fed mice

Article ID	Journal	Published Year	Pages	File Type
5501742	Free Radical Biology and Medicine	2017	31 Pages	PDF

Keywords

DCFH-DA CCCP cACT SOD2 MFN NOX4 acyl-coenzyme A oxidase 1 ACOX1 SREBP HMGCR POLG ACCα VDAC1 GPX ACADVL FAS PGC1 CAT Prdx AMPK 2′,7′-dichlorodihydrofluorescein diacetate AMP-activated protein kinase HMG-CoA reductase mtTFA NADPH oxidase 4 Fatty acid β-oxidation Kidney injury Apoe apolipoprotein E acetyl-CoA carboxylase alpha fatty acid synthase Mitochondrial biogenesis manganese-dependent superoxide dismutase Silymarin mitochondrial transcription factor A Obesity Mitofusin peroxisome proliferator-activated receptor gamma coactivator 1 Sterol regulatory element-binding protein Peroxiredoxin Catalase carnitine-acylcarnitine translocase carbonyl cyanide m-chlorophenylhydrazone glutathione peroxidase

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Silymarin protects against renal injury through normalization of lipid metabolism and mitochondrial biogenesis in high fat-fed mice

Authors

Bin Feng Bin Feng, Ran Meng, Bin Huang Bin Huang, Yan Bi, Shanmei Shen, Dalong Zhu,