• Daneshyari
  • Topics
    • Physical Sciences and Engineering
      Life Sciences
      Health Sciences
      Social Sciences and Humanities
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells

Article ID Journal Published Year Pages File Type
5501850 Free Radical Biology and Medicine 2016 13 Pages PDF
Abstract
Model: NOX4 stimulates glycolysis and supports glutaminolysis for resistance to apoptosis in NSCLC cells. The red, purple and green lines represented glycolysis, PPP and glutamine metabolism pathway, respectively.147
Keywords
LDHAPKM2PPPGSHNOX4GLSGLUT1GLNNADPH oxidase 4ROSNSCLCNon-small cell lung cancerOxidative phosphorylationLactate dehydrogenase Apentose phosphate pathwayPyruvate kinase M2Glutathioneglutathione synthetaseglutamineGlutaminaseGlutaminolysisglucose transporter 1GlycolysisReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells
Authors
Cheng Zeng, Qipeng Wu, Jing Wang, Bei Yao, Lei Ma, Zhicheng Yang, Juan Li, Bing Liu,
Related Articles
Cellular mechanisms underlying oxidative stress in human exercise
Regulation of NADPH oxidases in skeletal muscle
Muscle redox signalling pathways in exercise. Role of antioxidants
Exercise-induced ROS in heat shock proteins response
AMPK signaling in skeletal muscle during exercise: Role of reactive oxygen and nitrogen species
Regulation of myokine expression: Role of exercise and cellular stress
Regulation of exercise blood flow: Role of free radicals
Redox regulation of autophagy in skeletal muscle
Exercise-induced hormesis and skeletal muscle health
Mitohormesis in exercise training
Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
LDHA
PKM2
PPP
GSH
NOX4
GLS
GLUT1
GLN
NADPH oxidase 4
ROS
NSCLC
Non-small cell lung cancer
Oxidative phosphorylation
Lactate dehydrogenase A
pentose phosphate pathway
Pyruvate kinase M2
Glutathione
glutathione synthetase
glutamine
Glutaminase
Glutaminolysis
glucose transporter 1
Glycolysis
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
Daneshyari provides fulltext access to millions of research papers.