Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication

Article ID	Journal	Published Year	Pages	File Type
5501997	Free Radical Biology and Medicine	2017	56 Pages	PDF

Keywords

HO-1 ODQ NG-monomethyl-L-arginine CoPP BVR L-NMMA PKG Heme oxygenase-1 TFRC DCFH-DA iNOS PRRSV PAM NAC KT5823 ORF DFO Porcine alveolar macrophage Deferoxamine MARC-145 DMEM FBS 2′,7′-dichlorofluorescin diacetate MOI Dulbecco's modified Eagle's medium ROS Iron Antiviral effect Biliverdin biliverdin reductase Bilirubin fetal bovine serum african green monkey kidney cells inducible nitric oxide synthases open reading frame sodium nitroprusside Nitric oxide N-acetyl cysteine Hemoglobin Porcine reproductive and respiratory syndrome virus protein kinase G SNP Reactive oxygen species transferrin receptor

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Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication

Authors

Angke Zhang, Hong Duan, Na Li, Lijuan Zhao, Fengxing Pu, Baicheng Huang, Chunyan Wu, Yuchen Nan, Taofeng Du, Yang Mu, Qin Zhao, Yani Sun, Gaiping Zhang, Julian A. Hiscox, En-Min Zhou, Shuqi Xiao,