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An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle

Article ID Journal Published Year Pages File Type
5501999 Free Radical Biology and Medicine 2017 36 Pages PDF
Keywords
TFAMmitofusin-1PCXTRAP1Mitofusin-2MFFDNM1LMFN2Mfn1Fis1UCP2PINK1COXOXPHOSnDNACATMitochondrial DNANuclear DNAopa1PTEN-induced putative kinase 1ROSoptic atrophy 1mtDNAAgingcytochrome c oxidasemitochondrial transcription factor Amitochondrial fission factorMitochondrial oxidative phosphorylationMitochondriauncoupling protein 2pyruvate carboxylaseCatalaseLiverReactive oxygen species
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle
Authors
Jan Niemann, Cindy Johne, Susanne Schröder, Franziska Koch, Saleh M. Ibrahim, Julia Schultz, Markus Tiedge, Simone Baltrusch,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
TFAM
mitofusin-1
PCX
TRAP1
Mitofusin-2
MFF
DNM1L
MFN2
Mfn1
Fis1
UCP2
PINK1
COX
OXPHOS
nDNA
CAT
Mitochondrial DNA
Nuclear DNA
opa1
PTEN-induced putative kinase 1
ROS
optic atrophy 1
mtDNA
Aging
cytochrome c oxidase
mitochondrial transcription factor A
mitochondrial fission factor
Mitochondrial oxidative phosphorylation
Mitochondria
uncoupling protein 2
pyruvate carboxylase
Catalase
Liver
Reactive oxygen species
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
Related Journals
Neurobiology of Aging
Revista Española de Geriatría y Gerontología
Ageing Research Reviews
Archives of Gerontology and Geriatrics
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Experimental Gerontology
Journal of Geriatric Oncology
Journal of the Neurological Sciences
Maturitas
Mechanisms of Ageing and Development
Parkinsonism & Related Disorders
Redox Biology
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