Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells

Article ID	Journal	Published Year	Pages	File Type
5502040	Free Radical Biology and Medicine	2017	39 Pages	PDF

Keywords

MEFs sequestosome MG132 TRIS TrxR Trx p62 LC3 ATG AMPK BAF mTOR GSH ACC Nrf2 HEPES DMEM 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5′ AMP-activated protein kinase autophagy related MTT Autophagy SDS-PAGE Sodium dodecyl sulfate polyacrylamide gel electrophoresis Bafilomycin thioredoxin reductase thioredoxin HT22 cells Age Methylglyoxal Advanced glycation end products MgO mouse embryonic fibroblasts Mechanistic target of rapamycin Chloroquine UBI Glo Glutathione Glyoxalase Ubiquitin

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Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells

Authors

Alcir Luiz Dafre, Ariana Ern Schmitz, Pamela Maher,