Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation

Article ID	Journal	Published Year	Pages	File Type
5502208	Free Radical Biology and Medicine	2017	18 Pages	PDF

Keywords

NF-κB MSDI MDA ZO-1 CXCL1 3-NT Kelch-like ECH-associated protein-1 Heme oxygenase-1 BSCB NeuN IL-1β 8-OHdG GSSG MMP-9 ICAM-1 HO-1 Nrf2 GSH GFAP 3-nitrotyrosine 8-hydroxy-2’-deoxyguanosine keap1 MPO Iba-1 ROS Hydrogen peroxide Neuronal apoptosis Neuroinflammation ischemia-reperfusion interleukin 1β Oxidative stress tumor necrosis factor α SOD Superoxide dismutase antioxidant response element TNF-α nuclear factor erythroid 2-related factor 2 Nuclear factor-kappa B matrix metallopeptidase-9 malondialdehyde Blood-spinal cord barrier Methane ionized calcium-binding adaptor molecule 1 Intercellular adhesion molecule 1 myeloperoxidase Zonula occludens-1 ARE neuronal nuclei H2O2 Glial fibrillary acidic protein Glutathione glutathione disulfide Reactive oxygen species

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Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation

Authors

Liping Wang, Ying Yao, Rong He, Yan Meng, Na Li, Dan Zhang, Jiajun Xu, Ouyang Chen, Jin Cui, Jinjun Bian, Yan Zhang, Guozhong Chen, Xiaoming Deng,