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Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia

Article ID Journal Published Year Pages File Type
5502215 Free Radical Biology and Medicine 2017 46 Pages PDF
Abstract
Graphical summary showing the mechanisms mediating the activation of FOXO1 in quercetin-induced apoptosis and autophagy signal cascade.130
Keywords
PAHFOXO1RVSPPASMCsAutophagyPulmonary arterial smooth muscle cellspulmonary artery smooth muscle cellsPulmonary arterial hypertensionright ventricular systolic pressureHypoxiaQuercetin
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia
Authors
Yuanzhou He, Xiaopei Cao, Pujian Guo, Xiaochen Li, Huihui Shang, Jin Liu, Min Xie, Yongjian Xu, Xiansheng Liu,
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Journal
Free Radical Biology and Medicine
Journal: Free Radical Biology and Medicine
Related Categories
PAH
FOXO1
RVSP
PASMCs
Autophagy
Pulmonary arterial smooth muscle cells
pulmonary artery smooth muscle cells
Pulmonary arterial hypertension
right ventricular systolic pressure
Hypoxia
Quercetin
Ageing
Biochemistry
Biochemistry, Genetics and Molecular Biology (General)
Biophysics
Biotechnology
Cancer Research
Cell Biology
Clinical Biochemistry
Developmental Biology
Endocrinology
Genetics
Molecular Biology
Molecular Medicine
Physiology
Structural Biology
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