| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5502536 | Journal of the Neurological Sciences | 2017 | 24 Pages |
Abstract
This study shows a similar symptom spectrum, but distinct clinical and imaging findings in monozygotic twins suffering from SPG 11, suggesting individual downstream genetic effects and/or non-genetic modifiers.
Keywords
SPRSCMCTSPG11ADCTCSNaAMEPTBVMRSVolumetryCorpus callosumDTIN-Acetyl-AspartateFLAIRMRIradial diffusivityChodiffusion tensor imagingMagnetic resonance imagingtotal brain volumeCNSCentral motor conduction timecentral nervous systemCognitionapparent diffusion coefficientmagnetic resonance spectroscopygrey matterwhite matterMotor evoked potentialsMyo-inositolfractional anisotropyHereditary spastic paraplegiacreatineCholine
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Authors
Christiane Schneider-Gold, Gabriele Dekomien, Martin Regensburger, Ruth Schneider, Nadine Trampe, Christos Krogias, Carsten Lukas, Barbara Bellenberg,