Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5502706 | Journal of the Neurological Sciences | 2017 | 6 Pages |
Abstract
In summary, this is the first study in a Mexican population that considers the analysis of NR4A2 in patients with PD. An association was identified between genotype and mRNA expression levels of NR4A2 in patients with PD. These results suggest that polymorphisms and expression of the NR4A2 gene could play an important role in the risk of developing PD in Mexican populations.
Keywords
NR4A2PBMCHRMACDInDelUPDRSAICHWEASMAssociationacid citrate dextroseParkinson's diseaseHardy-Weinberg equilibriumHigh-resolution meltingperipheral blood mononuclear cellsconfidence intervalAkaike Information CriteriaUnified Parkinson's Disease Rating Scaleodd ratioHaplotypeAIMpolymerase chain reactionPCRPolymorphismsSingle nucleotide polymorphismSNPGenetics
Related Topics
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Elizabeth Ruiz-Sánchez, Petra Yescas, Mayela RodrÃguez-Violante, Nancy MartÃnez-RodrÃguez, Jesica N. DÃaz-López, Adriana Ochoa, Sergio S. Valdes-Rojas, Daniel Magos-RodrÃguez, Julio C. Rojas-Castañeda, Amin Cervantes-Arriaga,