| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5503539 | Maturitas | 2016 | 34 Pages |
Abstract
Aging is associated with altered mitochondrial morphological parameters and decreased mtDNA levels in oocytes, as well as an increase in ROS under stressful conditions and elevated expression of mitochondrial stress response gene Hspd1. Delineation of the mechanisms underlying mitochondrial changes associated with ageing may help in the development of diagnostic and therapeutic tools in reproductive medicine.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Elnur Babayev, Tianren Wang, Klara Szigeti-Buck, Katie Lowther, Hugh S. Taylor, Tamas Horvath, Emre Seli,