Article ID Journal Published Year Pages File Type
5503639 Mechanisms of Ageing and Development 2017 8 Pages PDF
Abstract
The budding yeast Saccharomyces cerevisiae has been used as a model organism for the study of aging for over 50 years. In this time, the canonical aging experiment-replicative lifespan analysis by manual microdissection-has remained essentially unchanged. Recently, microfluidic technologies have been developed that may be able to substitute for this time- and labor-intensive procedure. These technologies also allow cell physiology to be observed throughout the entire lifetime. Here, we review these devices, novel observations they have made possible, and some of the current system limitations.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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