| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5503706 | Mechanisms of Ageing and Development | 2017 | 32 Pages |
Abstract
The present findings confirm that HFD favors the formation of βA depositions in the brain, a key feature of AD, supporting the metabolic hypothesis of sporadic AD.
Keywords
AMPKT2DMBACE1Aβbeta-site APP-cleaving enzyme 1DIOIGF-1HCDHFDAMP-activated protein kinaseMAPKβ-Amyloidinsulin-like growth factor-1LoadAlzheimer’s diseaseAutonomic nervous systemType 2 diabetes mellitushigh-fat dietHigh calorie dietANSBBBbrain blood barrierCSFCerebrospinal fluidmitogen-activated protein kinasediet-induced obesity
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Oriol Busquets, Miren Ettcheto, Mercè Pallà s, Carlos Beas-Zarate, Ester Verdaguer, Carme Auladell, Jaume Folch, Antoni Camins,