Variable frequency stimulation of subthalamic nucleus in Parkinson's disease: Rationale and hypothesis

- Movement disorders are related with abnormal oscillations at different frequencies.
- Frequency is an important characteristic in brain stimulation therapies.
- High frequency stimulation only benefits certain motor symptoms in Parkinson's disease.
- Low frequency stimulation provides other selective symptomatic benefit in Parkinson's disease.
- Unlike a traditional fixed frequency stimulation method, a new pattern of variable frequency stimulation is proposed.