RNA editing of cytochrome c maturation transcripts is responsive to the energy status of leaf cells in Arabidopsis thaliana

•AtPAP2 interacts with all MORF proteins except MORF4 and MORF7.•We identified 34 and 510 RNA editing sites in chloroplast transcripts and mitochondrial transcripts, respectively.•Some sites in the transcripts of several cytochrome c maturation (Ccm) transcripts were differentially edited.•Western blotting of 2D BN-PAGE showed that the patterns of CcmFN1 polypeptides were different between the lines.•We proposed AtPAP2 may influence cytochrome c biogenesis by modulating RNA editing through its interaction with MORF proteins.

Overexpression of AtPAP2, a phosphatase located on the outer membranes of chloroplasts and mitochondria, leads to higher energy outputs from these organelles. AtPAP2 interacts with seven MORF proteins of the editosome complex. RNA-sequencing analysis showed that the editing degrees of most sites did not differ significantly between OE and WT, except some sites on the transcripts of several cytochrome c maturation (Ccm) genes. Western blotting of 2D BN-PAGE showed that the patterns of CcmFN1 polypeptides were different between the lines. We proposed that AtPAP2 may influence cytochrome c biogenesis by modulating RNA editing through its interaction with MORF proteins.