Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5521260 | Drug Discovery Today: Technologies | 2016 | 9 Pages |
Abstract
Site specific genome editing has been gradually employed in drug discovery and development process over the past few decades. Recent development of CRISPR technology has significantly accelerated the incorporation of genome editing in the bench side to bedside process. In this review, we summarize examples of applications of genome editing in the drug discovery and development process. We also discuss current hurdles and solutions of genome editing.
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Authors
Vidya Prabhu, Han Xu,