| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5524656 | Biomedical Journal | 2016 | 5 Pages |
Abstract
The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Jan Martel, Hsin-Chih Lai, Yun-Fei Ko, John D. Young, David M. Ojcius,