| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5524783 | Cancer Epidemiology | 2017 | 7 Pages |
Abstract
â¢This is the first case-control study ever conducted on Bangladeshi colorectal cancer patients in terms of TP53 codon 72 and CDH1 genetic polymorphisms.â¢Arg/Pro heterozygosity and Pro/Pro mutant homozygosity at codon 72 of TP53 shows a significant association for colorectal cancer predisposition.â¢A allele and combined genotype of C/A and A/A of CDH1 represent an elevated risk of colorectal cancer development.
Till now no pharmacogenetic study of TP53 codon 72 (Arg72Pro) and CDH1 rs16260 (-160C
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Sanzana Fareen Rivu, Mohd Nazmul Hasan Apu, Samia Shabnaz, Noor Ahmed Nahid, Md. Reazul Islam, Mir Md. Abdullah Al-Mamun, Zabun Nahar, Sikder Nahidul Islam Rabbi, Maizbha Uddin Ahmed, Mohammad Safiqul Islam, Abul Hasnat,