Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5531154 | Current Opinion in Cell Biology | 2017 | 7 Pages |
Abstract
Intracellular transport of organelles can be driven by multiple motor proteins that bind to the lipid membrane of the organelle and work as a team. We review present knowledge on how lipids orchestrate the recruitment of motors to a membrane. Looking beyond recruitment, we also discuss how heterogeneity and local mechanical properties of the membrane may influence function of motor-teams. These issues gain importance because phagocytosed pathogens use lipid-centric strategies to manipulate motors and survive in host cells.
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Authors
Divya Pathak, Roop Mallik,