Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5533056 | Immunobiology | 2016 | 4 Pages |
Abstract
Vitiligo is a common established depigmentation skin disease characterized by the presence of activated T lymphocytes anti melanocytes within the skin. T-cell immunity mainly mediates the destruction of melanocytes and is one of the main mechanisms involved in the pathogenesis of non-segmental vitiligo. Our previous study had identified several differentially expressed miRNAs and found that the expression of miR-3940-5p was downregulated in vitiligo patients. According to the research findings, we hypothesized that the novel miRNA plays a potential role on human cutaneous T lymphocytes in the action mechanism of immune imbalance in vitiligo.
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Authors
Yi Wang, Keyu Wang, Ningning Dang, Lihua Wang, Min Zhang,