| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5534856 | Seminars in Cell & Developmental Biology | 2017 | 10 Pages |
Abstract
Macrophages, named for their phagocytic ability, participate in homeostasis, tissue regeneration and inflammatory responses. Bone and adjacent marrow contain multiple functionally unique resident tissue macrophage subsets which maintain and regulate anatomically distinct niche environments within these interconnected tissues. Three subsets of bone-bone marrow resident tissue macrophages have been characterised; erythroblastic island macrophages, haematopoietic stem cell niche macrophages and osteal macrophages. The role of these macrophages in controlling homeostasis and repair in bone and bone marrow niches is reviewed in detail.
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Authors
Simranpreet Kaur, Liza Jane Raggatt, Lena Batoon, David Arthur Hume, Jean-Pierre Levesque, Allison Robyn Pettit,