| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5534947 | Seminars in Cell & Developmental Biology | 2017 | 7 Pages |
Abstract
â¢SoxB factors are key regulators of neural progenitor identity.â¢NCSC development is guided by Sox2.â¢Sox2 acts as the Guardian of the Developmental Clock.
Precise control of neural progenitor transformation into neural crest stem cells ensures proper craniofacial and head development. In the neural progenitor pool, SoxB factors play an essential role as cell fate determinants of neural development, whereas during neural crest stem cell formation, Sox2 plays a predominant role as a guardian of the developmental clock that ensures precision of cell flow in the developing head.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Nikolaos Panagiotis Mandalos, Eumorphia PhD,