Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5535004 | Seminars in Cell & Developmental Biology | 2016 | 13 Pages |
Abstract
Bacterial pathogens display an impressive arsenal of molecular mechanisms that allow survival in diverse host niches. Subversion of plasma membrane and cytoskeletal functions are common themes associated to infection by both extracellular and intracellular pathogens. Moreover, intracellular pathogens modify the structure/stability of their membrane-bound compartments and escape degradation from phagocytic or autophagic pathways. Here, we review the manipulation of host membranes by Listeria monocytogenes, Francisella tularensis, Shigella flexneri and Yersinia spp. These four bacterial model pathogens exemplify generalized strategies as well as specific features observed during bacterial infection processes.
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Authors
Javier Pizarro-Cerdá, Alain Charbit, Jost Enninga, Frank Lafont, Pascale Cossart,