Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5536869 | Vaccine | 2017 | 6 Pages |
Abstract
These results, together with other data from repeat-dose toxicity and neurovirulence studies, confirm the absence of toxicological concern with CYD-TDV and corroborate clinical study observations.
Keywords
qRT-PCRCYD-TDVDHFDENVNHPsDSSPBSLLOQDengue hemorrhagic feverDengue feverYellow feverELISAEnzyme-linked immunosorbent assayBiodistributionlower limit of quantificationDengueSheddingsubcutaneousWorld Health OrganizationToxicityDengue shock syndromePhosphate buffered salinecynomolgus monkeywild-typeLive attenuated vaccineQuantitative reverse transcriptase polymerase chain reactionDengue virusNon-human primatesWHO
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Authors
Guillaume Ravel, Nathalie Mantel, Jeremy Silvano, Alexandra Rogue, Bruno Guy, Nicholas Jackson, Nicolas Burdin,