Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5537268 | Vaccine | 2017 | 4 Pages |
Abstract
We assessed the cost-effectiveness of offering catch-up vaccination with Bexsero against meningococcal disease to children too old to receive the vaccine under the recently introduced infant programme. Offering catch-up vaccination to increasingly older children is less economically attractive because of declining disease burden. We estimate catch-up vaccination of 1 year old children could be cost-effective, incremental on the infant programme with a vaccine price of ⩽£8 per dose. Extending vaccination to 2 year olds could only be cost-effective (incremental on infant and 1 year old catch-up) with a vaccine price of ⩽£3 per dose and was not cost-effective in sensitivity analyses with more conservative vaccine assumptions. Extending catch-up further to 3-4 year olds was not cost-effective. Employing the current criteria for assessing vaccines, our models suggest that even with low vaccine prices only catch-up vaccination in 1 year old children could be cost-effective, when considered incrementally on the infant programme.
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Authors
Hannah Christensen, Caroline L. Trotter,