Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic country

Article ID	Journal	Published Year	Pages	File Type
5537282	Vaccine	2017	8 Pages	PDF

Abstract

Our results suggest that ASC/ALS responses to two doses of the oral cholera vaccine Dukoral and related oral vaccines should be analyzed earlier than previously recommended (day 7) at all ages. Fecal antibody responses should preferably be analyzed later than ASC/ALS responses to detect the highest antibody responses.

Keywords

CFS PBMCs ASC LTB CTB ETEC Aes enterotoxigenic Escherichia coli sIgA antibody-secreting cell IgA ALS Secretory IgA Membrane preparation peripheral blood mononuclear cells Heat labile toxin cholera toxin Adverse events Colonization factors Oral vaccine Cholera cholera toxin B-subunit Children

Related Topics

Life Sciences Immunology and Microbiology Immunology

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Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic country

Authors

Marjahan Akhtar, Firdausi Qadri, Taufiqur R. Bhuiyan, Sarmin Akter, Tanzeem A. Rafique, Arifuzzaman Khan, Laila N. Islam, Amit Saha, Ann-Mari Svennerholm, Anna Lundgren,