Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5539975 | Developmental & Comparative Immunology | 2017 | 31 Pages |
Abstract
The use of large scale DNA/RNA sequencing has become an integral part of biomedical research. Reduced sequencing costs and the availability of efficient computational resources has led to a revolution in how problems concerning genomics and transcriptomics are addressed. Sequencing-based pathogen discovery represents one example of how genetic data can now be used in ways that were previously considered infeasible. Emerging pathogens affect both human and animal health due to a multitude of factors, including globalization, a shifting environment and an increasing human population. Fish farming represents a relevant, interesting and challenging system to study emerging pathogens. This review summarizes recent progress in pathogen discovery using sequence data, with particular emphasis on viruses in Atlantic salmon (Salmo salar).
Keywords
Salmon alphavirusHSMIIPNVVHSVSAVISAVVACVHSsVHSIPNGSSCMSENASSHDDBJDNA Data Bank of JapanPiscine orthoreovirusPRVESTEuropean Nucleotide ArchivePancreas diseaserapid amplification of cDNA endsgenome survey sequenceNext generation sequencingExpressed sequence tagsSalmo salarViral hemorrhagic septicemiaAtlantic salmonPdGRaceInfectious pancreatic necrosisISASuppression subtractive hybridizationviral hemorrhagic septicemia virusInfectious salmon anemia virusInfectious pancreatic necrosis virusvaccinia virusInfectious salmon anemia
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Authors
Torstein Tengs, Espen Rimstad,