| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5548429 | Medical Hypotheses | 2017 | 4 Pages |
Abstract
Inflammatory eye diseases such as uveitis are common and may eventually result in vision loss. Iron can play a critical role in ocular inflammation via promoting the generation of oxygen free radicals and it is also nutritionally essential for microbial growth. Considering this involvement of iron in inflammation and microbial infection, we hypothesize that administration of iron chelators has potential to function as a novel therapy in uveitis and help improve clinical outcomes.
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Authors
Junru Chen, Juan Zhou, Mel Kelly, Bruce E. Holbein, Christian Lehmann,