Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells

Article ID	Journal	Published Year	Pages	File Type
5552613	Biomedicine & Pharmacotherapy	2017	7 Pages	PDF

Abstract

The data obtained during the study demonstrated that overexpression of FADD and Caspase-8 suppresses proliferation whilst promoting the apoptosis of human GBM cells.

Keywords

DR5 FCM DED FADD DISC GBM HRP qRT-PCR Cell apoptosis Sodium dodecyl sulfate polyacrylamide gel electrophoresis standard deviation Overexpression Cell proliferation death domain death effector domain Flow cytometry quantitative real-time polymerase chain reaction horse radish peroxidase Fas-associated protein with death domain death-inducing signaling complex optical density negative control Glioblastoma death receptor 5