| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5556960 | Life Sciences | 2017 | 9 Pages |
Abstract
Sickle Cell Anemia (SCA) was one of the first hemoglobinopathies to be discovered. It is distinguished by the mutation-induced expression of a sickle cell variant of hemoglobin (HbS) that triggers erythrocytes to take a characteristic sickled conformation. The complex physiopathology of the disease and its associated clinical complications has initiated multi-disciplinary research within its field. This review attempts to lay emphasis on the evolution, current standpoint and future scope of therapeutic strategies in SCA.
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Authors
Queenie Fernandes,