Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5557984 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2017 | 7 Pages |
Abstract
We identified no significant predictive effect using PRS between pharmacogenetic studies. The genetic liability to MDD or schizophrenia did not predict response to antidepressants, suggesting differences between the genetic component of depression and treatment response. Larger or more homogeneous studies will be necessary to obtain a polygenic predictor of antidepressant response.
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Authors
Judit GarcÃa-González, Katherine E. Tansey, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Ole Mors, Anna Placentino, Marcella Rietschel, Daniel Souery, Tina Žagar, Piotr M. Czerski, Borut Jerman, Henriette N. Buttenschøn, Thomas G. Schulze,