| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5558029 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2017 | 8 Pages |
Abstract
The higher Glx levels in patients with lifetime AVH as compared to patients without lifetime AVH suggest a mediating role for Glx in AVH. Our results are consistent with a previous study that found similar decreased levels of Glx in patients with schizophrenia, and increased levels in an AVH group as compared to a NoAVH group. The role of the glutamatergic system deserves further investigation, for example in different brain regions and in relation to clinical variables.
Keywords
AVH1H MRSPANSSDLPFCn.s.FWHMSNRANCOVAGlxSchizophreniahealthy control subjectsanalysis of covarianceanalysis of varianceANOVAAuditory verbal hallucinationsMagnetic resonance spectroscopy (MRS)Proton magnetic resonance spectroscopyfull width half maximumdorso-lateral prefrontal cortexgrey matterCSFCerebrospinal fluidPRESSpositive and negative syndrome scalenot significantpoint resolved spectroscopyglutamate
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Authors
Branislava ÄurÄiÄ-Blake, Leonie Bais, Anita Sibeijn-Kuiper, Hendrika Maria Pijnenborg, Henderikus Knegtering, Edith Liemburg, André Aleman,