Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5558181 | Pulmonary Pharmacology & Therapeutics | 2017 | 6 Pages |
Abstract
PBPK software modelling correlates well with clinical data. Current aminophylline iv loading dosage recommendations achieve levels <10Â mg/l in 70% of children. Routine TDM may need altering as low risk of toxicity (>20Â mg/l).
Related Topics
Health Sciences
Medicine and Dentistry
Pulmonary and Respiratory Medicine
Authors
Lewis Cooney, Antonia McBride, Andrew Lilley, Ian Sinha, Trevor N. Johnson, Daniel B. Hawcutt,