Glycyrrhetinic acid attenuates lipopolysaccharide-induced fulminant hepatic failure in d-galactosamine-sensitized mice by up-regulating expression of interleukin-1 receptor-associated kinase-M

Article ID	Journal	Published Year	Pages	File Type
5558444	Toxicology and Applied Pharmacology	2017	34 Pages	PDF

Keywords

D-GalN FHF TRAF TLR4 interleukin-1 receptor-associated kinases ALT LBP qRT-PCR MYD88 MD2 myeloid differentiation factor LPS d-Galactosamine MAPKs AST Aspartate aminotransferase Alanine aminotransferase Glycyrrhetinic acid ELISA Enzyme-linked immunosorbent assay tumor necrosis factor-α Fulminant hepatic failure myeloid differentiation factor 2 IRAKs IRAK-M TNFR-associated factor TNF-α lipopolysaccharide Toll like receptor 4 quantitative reverse transcription-polymerase chain reaction LPS-binding protein mitogen-activated protein kinases

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Glycyrrhetinic acid attenuates lipopolysaccharide-induced fulminant hepatic failure in d-galactosamine-sensitized mice by up-regulating expression of interleukin-1 receptor-associated kinase-M

Authors

Xinru Yin, Xia Gong, Li Zhang, Rong Jiang, Ge Kuang, Bin Wang, Xinyu Chen, Jingyuan Wan,