Article ID Journal Published Year Pages File Type
5560887 NeuroToxicology 2017 8 Pages PDF
Abstract

•Manganese occupational exposure limits (OELs) vary among organizations.•Guidance is provided for the selection of relevant and reliable OELs for manganese.•Three recent OELs were found to be quantitatively similar and equally reliable.•Similarities in the differently-derived OELs increases confidence in recent values.

Occupational exposure limits (OELs) serve as benchmarks for the interpretation of workplace exposures within a health risk context. Different organizations derive OELs for many chemicals, including manganese. OELs recommended by different organizations can vary quantitatively, which can present a challenge to occupational hygienists or other risk managers that need to select a value for decision-making purposes. In this article, we illustrate the application of a previously-developed OEL selection framework to demonstrate the decisions that would be required to select the most appropriate OEL for various manganese exposure scenarios. The framework helped to identify the need to focus an evaluation on three quantitatively similar values-the ACGIH TLV, SCOEL IOELV, and DFG MAK. These values were compared with regulatory standards and considered for their relevance and reliability. The OEL selection framework was a useful tool in guiding the selection process for manganese OELs.

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Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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