| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5561415 | Reproductive Toxicology | 2017 | 37 Pages |
Abstract
The development of new angiogenic inhibitors highlights a need for robust screening assays that adequately capture the complexity of vessel formation, and allow for the quantitative evaluation of the teratogenicity of new anti-angiogenic agents. This review discusses the use of screening assays in vertebrate embryos, specifically focusing upon chicken and zebrafish embryos, for the detection of anti-angiogenic agents.
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Authors
Shaunna L. Beedie, Alexandra J. Diamond, Lucas Rosa Fraga, William D. Figg, Neil Vargesson,