| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5561723 | Toxicology | 2017 | 35 Pages |
Abstract
In summary, our data implies sex-dependent effect of OTA, with males being more sensitive. The lack of Nrf2 enhances susceptibility to mycotoxin-induced pathologies, suggesting that modulation of the Nrf2 pathway may provide a therapeutic approach to treat OTA-triggered renal diseases.
Keywords
Heme oxygenase-1SFNOTABENTGFβHO-1Nrf2γ-GTPThe International Agency for Research on CancerLLC-PK1RPTECROSγ-glutamyltranspeptidaseAlkaline phosphataseIARC یا International Agency for Research on CancerOchratoxin Akidney diseasesTransforming growth factor βEMTRoom temperatureSulforaphanenuclear factor E2-related factor 2Vascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)lactate dehydrogenaseLDHMycotoxinMicroRNANephrotoxicityBalkan endemic nephropathyReactive oxygen species
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Authors
Agnieszka Loboda, Anna Stachurska, Mateusz Sobczak, Paulina Podkalicka, Olga Mucha, Alicja Jozkowicz, Jozef Dulak,