Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

Article ID	Journal	Published Year	Pages	File Type
5561865	Toxicology	2017	12 Pages	PDF

Keywords

NF-κB H12 AMPKα Dioscin Hemeoxygenase-1 FXR HMGB1 IL-1β HO-1 GST Nrf2 DOX IL-6 Small interfering RNA siRNA inflammation interleukin-6 Interleukin-1β Oxidative stress tumor necrosis factor alpha BUN Doxorubicin NF-E2-related factor 2 TNF-α nuclear factor kappa B Nephrotoxicity blood urea nitrogen High mobility group box 1 creatinine glutathione-S-transferase

Related Topics

Life Sciences Environmental Science Health, Toxicology and Mutagenesis

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

Authors

Yimeng Zhang, Youwei Xu, Yan Qi, Lina Xu, Shasha Song, Lianhong Yin, Xufeng Tao, Yuhong Zhen, Xu Han, Xiaodong Ma, Kexin Liu, Jinyong Peng,