| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5562314 | Toxicology Letters | 2016 | 12 Pages |
Abstract
No induction of DNA damage was observed after any MWCNTs in any cell line by the comet assay, while the micronucleus assay revealed that both NM-401 and NM-402 were genotoxic in A549 cells. NM-401 and NM-402 are the two longest MWCNTs analyzed in this work, suggesting that length may be determinant for genotoxicity. No induction of micronuclei was observed in BBEAS-2Beas-2B cell line and the different effect in both cell lines is explained in view of the size-distribution of MWCNTs in the cell culture medium, rather than cell's specificities.
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Authors
Henriqueta Louro, Mariana Pinhão, Joana Santos, Ana Tavares, Nádia Vital, Maria João Silva,