| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5562724 | Toxicology in Vitro | 2017 | 37 Pages |
Abstract
The VITROCELL® VC10® provided consistent generation and delivery of whole smoke; exposure-related changes in in vitro cytotoxicity were observed with reproducible IC50 values; comparative analysis showed that the heat-not-burn cigarette was significantly (PÂ <Â 0.001) less cytotoxic than the 3R4F combustible cigarette, consistent with the lower levels of chemical constituents liberated by primarily-heating the cigarette versus burning.
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Authors
Wanda Fields, Kathy Fowler, Victoria Hargreaves, Lesley Reeve, Betsy Bombick,